Local Anesthetic Toxicity Calculator
Result
Toxicity Risk Safe
Maximum Safe Dose 490 mg
Actual Dose Administered 3 mg
Safety Margin 99.4%
Calculate safe dosing for local anesthetics and assess toxicity risk. Clinical reference tool for healthcare providers to ensure anesthetic doses remain within safe limits based on patient weight and agent used.
Formula
Max Dose = min(Weight × Agent Limit, Absolute Maximum); Safety Margin = (Max - Actual) ÷ Max × 100%
- Lidocaine: 7 mg/kg (500mg with epinephrine, 350mg without)
- Bupivacaine: 2.75 mg/kg (175mg max)
- Prilocaine: 8 mg/kg (600mg max)
Lidocaine Infiltration
Inputs
- Patient Weight (kg): 70 kg
- Anesthetic Agent: lidocaine
- Concentration (%): 1 %
- Volume Administered (mL): 30 mL
- Epinephrine Added: yes
70kg patient, 30mL 1% lidocaine with epinephrine = 300mg. Max 490mg. Safety margin 38.8% = SAFE.
Frequently asked questions
What if margin is negative?
Do NOT administer - dose exceeds safe limit. Toxicity risk (seizures, cardiac events). Consult anesthesia.