Lille Score

Patient age
At start of therapy
After 7 days of therapy
Prothrombin time
After 7 days
At 7 days
At 7 days
Health

Calculate Lille Score to predict response to corticosteroid therapy in severe alcoholic hepatitis. Score 0.45 is cutoff: score >0.45 indicates non-responder.

Rates and fees change frequently. Always confirm the current figures with the official authority before relying on this result.

Formula

Lille = e^x / (1 + e^x), where x uses bilirubin ratio, age, albumin, creatinine
  • Predicts corticosteroid response in severe alcoholic hepatitis; cutoff 0.45; requires specialist interpretation

Lille Score

Inputs
  • Age (years): 50
  • Baseline Bilirubin (mg/dL): 15
  • Day 7 Bilirubin (mg/dL): 12
  • Baseline PT (seconds): 18
  • Day 7 PT (seconds): 16
  • Day 7 Albumin (g/dL): 2.8
  • Day 7 Creatinine (mg/dL): 1.2

Score 0.55 indicates non-responder with poor prognosis requiring alternative therapy

Frequently asked questions

What does Lille >0.45 mean?
Non-responder; poor prognosis; consider discontinuing corticosteroids and alternative therapy.
What does Lille ≤0.45 mean?
Responder; continue corticosteroid therapy; improved 6-month survival expected.
Is this a definitive predictor?
Lille is a validated prognostic score but should be used alongside clinical judgment; consult hepatology specialist.